Coumarins and derivatives
Apexbio Technology LLC Palomid 529 914913-88-5 10mg
Palomid 529 (CAS 914913-88-5) is a small-molecule inhibitor of the PI3K/Akt/mTOR signaling pathway targeting both TORC1 and TORC2 complexes It exhibits potent anti-proliferative activity in the NCI-60 cell line panel with GI50 values below 35 M In endothelial cell assays Palomid 529 inhibits VEGF- and bFGF-induced proliferation with IC50 values of 20 nM and 30 nM respectively The PI3K/Akt/mTOR pathway is implicated in tumor cell survival proliferation angiogenesis and resistance to apoptosis Palomid 529 has also demonstrated the ability to suppress radiation-induced expression of Id-1 VEGF MMP-2 and MMP-9 expanding its utility in studies of cancer biology and radiotherapy sensitization
eMolecules 2442-31-1 | Medchem Express | 8-Hydroxycoumarin | 100mg | 572596935 | HY-21509 | MFCD18450722 | 162.144 | C9H6O3
ChemScene | Methyl [22-bipyridine]-5-carboxylate | 100mg | 687420685 | CS-0371260 | 58792-53-3 | 214.224 | C12H10N2O2
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Chem-Impex International, Inc. 4-Methylumbelliferyl phosphate disodium salt | 22919-26-2 | MFCD00037614 | 1G
4-Methylumbelliferyl phosphate disodium salt, 22919-26-2, MFCD00037614, 1G
Selleck Chemical LLC Psoralen S4737-10mg
Psoralen (Psoralene Ficusin Furocoumarin) is a naturally occurring furocoumarin that intercalates with DNA inhibiting DNA synthesis and cell division
Selleck Chemical LLC Dicoumarol S4299-200mg
Dicoumarol is a competitive NADPH quinone oxidoreductase (NQO1) inhibitor and used as an anticoagulant by interfering with the metabolism of vitamin K
Medchemexpress LLC Coumarin 7 | 27425-55-4 | MFCD00051348 | 99.8% | 333.4 g/mol | C20H19N3O2 | 50MG
Coumarin 7 is a coumarin-class laser dye supplied as a high-purity solid for research applications. It is used as a fluorescent probe and laser medium in spectroscopy, fluorescence studies, and related dye research, and is provided in small, laboratory-scale quantities. Intended for research use only.
- Laser-active coumarin dye with strong fluorescence.
- High purity (99.8%) suitable for analytical and research applications.
- Provided in mg-scale quantities for laboratory experiments.
- Solid powder form, easy to weigh and dissolve in common organic solvents.
- Intended for research use only.
eMolecules 3-(ETHYLAMINO)PROPANAMIDE HCL | 2044705-01-1 | MFCD29924219 | 1g
AstaTech | 3-(ETHYLAMINO)PROPANAMIDE HCL | 1g | 596576136 | AT24732 | 95.000 | 2044705-01-1 | MFCD29924219 | 152.620 | C5H13ClN2O
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Medchemexpress LLC Coumarin 6H | 58336-35-9 | 99.6% | 1 ML
Coumarin 6H is a coumarin-family laser dye supplied as a high-purity solid or as a 10 mM solution in dimethyl sulfoxide (DMSO). It exhibits strong fluorescence that can be enhanced through hydrogen-bonding interactions, making it suitable for laser dye and fluorescence applications.
- Available as 10 mM solution in DMSO or as solid quantities (50 mg-1 g).
- High purity, typically 99.6%.
- Molecular formula C15H15NO2 and molecular weight 241.29 g·mol^-1.
- Fluorescence emission enhanced by hydrogen bonding interactions.
- Soluble in common organic solvents such as DMSO.
- Intended for use as a laser dye and fluorescent probe in optical applications.
Cayman Chemical 3azido7hydroxy Coumarin
A click-reactive fluorescent dye; Upon CuAAC in a biological system, a fluorescent product is produced that displays excitation/emission maxima of 404 and 477 nM, respectively; has been used for spatially restricted metabolite labeling and the detection of foodborne pathogens
Selleck Chemical LLC Esculetin S4711-1g
Esculetin (Cichorigenin Aesculetin) is a coumarin derivative found in various natural plant products with various biological and pharmaceutical properties including anti-edema anti-inflammatory and anti-tumour effects It inhibits lipoxygenases (LOs)
Medchemexpress LLC 7-methoxycoumarin-3-carboxylic acid | 20300-59-8 | MFCD00452770 | 97.0% | 220.18 | C11H8O5 | 250 MG
7-Methoxycoumarin-3-carboxylic acid is a coumarin-based fluorescent dye used to derivatize molecules for fluorescence detection in biochemical assays. It is commonly applied to label peptides, for HPLC derivatization, and for development of fluorescent probes.
- Fluorescent coumarin dye with characteristic excitation and emission peaks.
- Excitation ~345-355 nm; emission ~405-450 nm.
- High purity (manufacturer lists 97.0%).
- Chemical formula C11H8O5; molecular weight 220.18.
- Available in multiple sizes from 250 mg to 50 g.
- Suitable for peptide labeling and HPLC derivatization.
- Supplied with data sheet and safety data sheet (SDS).
eMolecules 84227-70-3 | (4-Aminomethylbenzyl)diethylamine | MFCD07343995 | 1g
Combi-Blocks | (4-Aminomethylbenzyl)diethylamine | 1g | 117572923 | ST-6479 | 95.000 | 84227-70-3 | MFCD07343995 | 192.306 | C12H20N2
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